2024
Doctoral Thesis Defense: "Multifunctional Nanoparticles for Controlled Enzyme Delivery", by Andrea Montero Oleas
November 8, 2024
On Friday, November 8th, the defense of the doctoral thesis titled "Multifunctional Nanoparticles for Controlled Enzyme Delivery" took place, presented by Andrea Montero Oleas. The project was carried out as part of a joint supervision between the School of Chemistry and Life Sciences at the University of Grenoble Alpes and the DQIAQF at the University of Buenos Aires (UBA).
The thesis was supervised by Dr. Sara Aldabe Bilmes, co-supervised by Dr. Xavier Cattoën, and Dr. Ernesto Marceca acted as the Study Advisor. The jury members were Dr. Fernando Battaglini (Associate Professor, DQIAQF, FCEN, UBA – Senior Researcher, INQUIMAE, CONICET), Dr. Marcelo Kogan (Associate Professor, University of Chile), Dr. Verónica Cortez de Zea Bermúdez (Associate Professor, University of Trás-os-Montes and Alto Douro, Portugal), Dr. Belén Albela (Assistant Professor, Ecole Normale Supérieure de Lyon, France), and Dr. Eric Peyrin (Associate Professor, Université Grenoble Alpes).
Summary:
This thesis presents the design of a nanocarrier based on mesoporous silica nanoparticles with a gold core (Au@mSiO₂) for the controlled delivery of proteins. The design was based on the study of the nanoparticle synthesis mechanism, which allowed the development of a robust synthesis pathway for Au@mSiO₂ with large pores, ideal for accommodating proteins and with an optimal size for transport in biological media.
The efficiency of the nanoparticles for protein retention was analyzed using model proteins to describe the retention process. It was observed that both the pore size and the protein structure influenced the retention efficiency and the stability of the retained proteins.
Finally, the response of the nanocarrier to light stimulation was studied. The efficiency of the plasmonic heating of Au@mSiO₂ was characterized, and the resulting temperature increase was determined.
Congratulations, Andrea!
13th NanoAndes School “Saúl Cabrera” -
Bolivia 2024
November 11-15, 2024
The NanoAndes Network is pleased to announce the call for the 13th NanoAndes School "Saúl Cabrera" and the NanoAndes Bolivia 2024 Workshop, prominent events in the field of Nanosciences and Nanotechnologies to be held in La Paz, Bolivia.
The 13th NanoAndes School "Saúl Cabrera" invites young researchers from Latin America and France to participate by presenting their research in nanosciences and nanotechnologies. This event is aimed at undergraduate, master’s, doctoral, and postdoctoral students, as well as researchers who have recently completed their postgraduate studies.
11th Synthesis of Nanostructured Materials School: Sol-Gel Processes
September 23 - October 4, 2024
On September 23, a new edition of the Sol-Gel School will begin at the 'Miguelete' Campus of the National University of San Martín.
This School has been held biennially since 2003. It has contributed to the training of over 500 Ph.D. students in the area of material synthesis via chemical methods, by combining theorical, and laboratory knowledge. The School has become an important reference for building a community focus on materials chemistry and nanotechnology over the past two decades and has inspired other courses that have emerged in the Americas and Europe.
4th Workshop on Coated Tools
& Multifunctional Thin Films 2024
August 19-23, 2024
Dr. María Claudia Marchi and Prof. Dr. Sara Aldabe Bilmes have participated in the conference "4th Workshop on Coated Tools & Multifunctional Thin Films 2024 Campinas - Brasil”, organized by the University of Campinas (Brazil), Guangdong University of Technology (China), and the University of Nantes (France).
